CD21 Antigen

The CD21 molecule is a 145 kDa type I transmembrane glycoprotein, which belongs to the family of complement regulatory proteins. CD21 is expressed by mature B lymphocytes and is rapidly lost following cellular activation. It is not expressed on early (pre-B) and late (B blast or plasma cell) B ontogeny. On follicular dendritic cells the CD21 antigen is strongly expressed. Expression of CD21 in a subset of T lymphocytes has been reported. Four types of CD21 ligands have been identified: They are products following proteolytic cleavage of the complement protein C3 (i. e. iC3b, C3dg and C3d), the Epstein-Barr (EBV) virus envelope, Interferon α (IFNα) and CD23. CD21 was found to be part of a large complex containing also CD19, and CD81 (also named TAPA-1) suggesting a key-role of CD21 during the immune response.


 Clone: BL13  Isotype: IgG1 Mouse

 

Explore Beckman Coulter CD21 Conjugated Antibodies

Part Number Product Name Status Clone Size List Price Buy
ASR
BL13
0.5 mL

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ASR
BL13
2 mL

-

ASR
BL13
2 mL

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Product Line Specifications

Format Liquid
Specificity CD21
Form Pacific Blue*
Clone BL13
Isotype IgG1 Mouse
Target Species Human
Flow Product Line IOTest
Item Specifications Referenced B09982

The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent. 


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