CD8 Antigen

The CD8 antigen is a disulfide-linked dimer, which exists either as a CD8α homodimer or as a CD8α/β heterodimer. CD8α is required for surface expression of CD8β. The molecular weight of each monomer of α or β is approximately 32-34 kDa. CD8 binds to a non-polymorphic domain (α3 domain) of MHC Class I molecules. CD8 is expressed on a subset of human peripheral blood T lymphocytes. A subset of NK cells possess the CD8 antigen but show low to medium density of expression. CD8α homodimer is expressed by NK cells and γ/δ+ T cells. CD8 is also present on most thymocytes where it is frequently co-expressed with CD4, and on a subpopulation of bone marrow cells. The CD8 molecule acts with the T Cell Receptor (TCR) as a coreceptor for MHC class I restricted antigen recognition. CD8 is widely used as a marker of cytotoxic T lymphocytes.


Clone: B9.11  Isotype: IgG1 Mouse

The B9.11 monoclonal antibody recognizes the α chain of the CD8 molecule. It was used as a CD8 reference monoclonal antibody during HLDA 6 (ref. 6T-CD8.5).

Clone: 2SFCI21Thy2D3 (T8) Isotype: IgG1 Mouse

SFCI21Thy2D3 monoclonal antibody recognizes the α chain of the CD8 molecule.

 

Explore Beckman Coulter CD8 Conjugated Antibodies

Part Number Product Name Status Clone Size List Price Buy
ASR
B9.11
0.5 mL

-

ASR
B9.11
0.5 mL

-

ASR
B9.11
0.5 mL

-

CE
B9.11
50 Tests

-

CE
B9.11
50 Tests

-

ASR
B9.11
0.5 mL

-

CE
B9.11
100 Tests

-

CE
B9.11
100 Tests

-

CE
B9.11
100 Tests

-

ASR
B9.11
0.5 mL

-

CE
SFCI21Thy2D3
50 Tests

-

CE
SFCI21Thy2D3
100 Tests

-

ASR
SFCI21Thy2D3
0.5 mL

-

IVD, CE
SFCI21Thy2D3
100 Tests

-

IVD, CE
SFCI21Thy2D3
50 Tests

-

IVD, CE
SFCI21Thy2D3
100 Tests

-

RUO
SFCI21Thy2D3
100 Tests

-

ASR
SFCI21Thy2D3
0.5 mL

-

ASR
B9.11
0.5 mL

-

ASR
SFCI21Thy2D3
0.5 mL

-

ASR
SFCI21Thy2D3
0.5 mL

-

ASR
B9.11
0.5 mL

-

CE
B9.11
50 Tests

-

ASR
B9.11
1 mL

-

ASR
B9.11
1 mL

-

CE
B9.11
100 Tests

-

ASR
B9.11
2 mL

-

ASR
B9.11
2 mL

-

Product Line Specifications

Format Liquid
Specificity CD8
Form Alexa Fluor* 700
Clone B9.11
Isotype IgG1 Mouse
Target Species Human
Flow Product Line IOTest
Item Specifications Referenced B76279

The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent. 


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