CD106 Antigen

The CD106 antigen, also known as Vascular Cell Adhesion Molecule-1 (VCAM-1), is an adhesion molecule which binds to integrin α4/β1 (VLA-4) and integrin α4/β7 on lymphocytes. It is a 110 kDa cell surface sialoglycoprotein belonging to the immunoglobulin superfamily. CD106 contains 7 Ig-like C2-type (immunoglobulin-like) domains. CD106 antigen is present on activated endothelial cells, tissue macrophages, dendritic cells and bone marrow fibroblasts. It is involved in the adhesion of lymphocytes, monocytes and eosinophils to activated endothelium. Recent studies shown that CD106 identifies a unique subpopulation of Mesenchymal Stem Cells (MSCs) with powerful immunosuppressive activity.


 Clone: 1G11  Isotype: IgG1 Mouse

The 1G11 antibody inhibits T lymphocyte adhesion to TNF-stimulated endothelial cells.
 

 

Explore Beckman Coulter CD106 Conjugated Antibodies

Part Number Product Name Status Clone Size List Price Buy
RUO
1G11
100 Tests

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Product Line Specifications

Format Liquid
Specificity CD106
Form PE
Clone 1G11
Isotype IgG1 Mouse
Target Species Human
Flow Product Line IOTest
Item Specifications Referenced A66085

The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent. 


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